Therapies targeting the programmed cell death protein-1/programmed death-ligand 1 (PD-L1) (abbreviated as PD-(L)1) axis are a significant advancement in the treatment of many tumor types.However, Jewelry Sets many patients receiving these agents fail to respond or have an initial response followed by cancer progression.For these patients, while sub
Bowel and bladder anxiety: An obsession or a variant of agoraphobia?
It Mini Bowl has long been debated whether bowel and bladder anxiety are a part of obsessive compulsive spectrum disorder or a variant of agoraphobia with no consensus view yet.Tricyclic antidepressants are reportedly efficacious in such cases and lead to complete resolution of symptoms.Here, we report a 36-year-old male having urges to visit toile
hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure.
After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling.A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation.We hypothesized that in a rat model of MI-induced chronic heart failure, this therapy could be fu
Managing IMS Learning Design
Commentary on: Chapter 15: How to Integrate Learning Design into Existing Practice.(Janssen & Hermans, 2005) Abstract: Taking IMS Learning Design (LD) beyond the domain of researchers and programmers, this short paper looks at some of the challenges of mainstreaming it within institutional strategies, processes, and cultures.The experiences 6-06 N